Antisense technology in the central nervous system

1. Antisense oligonucleotide regulation of gene expression in the CNS: an overview 2. Antisense knockdown in the CNS - optimizing the strategy 3. The design of appropriate control experiments to ensure specificity in antisense oligonucleotide function 4. Modulation of gene expression in the central nervous system as a tool in behavioral pharmacology 5. Behavioural and neuroendocrine effects of antisense targeting in the rat 6. Electrophysiological and behavioural effects of dopamine receptor knockdown in the brain 7. Medicinal chemistry of antisense oligonucleotides 8. Retinal neuronal development in trkB antisense 'knockdowns' 9. Pluronic gel as a means of antisense delivery