General Method for Selective Mono-Boc Protection of Diamines and Thereof
2017
Here we report a simple and efficient protocol for selectively diamine protection with Boc using Me 3 SiCl or SOCl 2 as HCl source in “one-pot” procedure. This methodology is extended to 1,2- to 1,8-diamines to obtain the corresponding mono-Boc protected diamines.
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