Haploinsufficiency of the paternal-effect gene Dnmt3L results in transient DNA hypomethylation in progenitor cells of the male germline

Kirsten M. Niles,Jonathan R. Yeh,Donovan Chan,Mylène Landry,Makoto C. Nagano,Jacquetta M. Trasler

Haploinsufficiency of the paternal-effect gene Dnmt3L results in transient DNA hypomethylation in progenitor cells of the male germline

2013

Kirsten M. Niles
Jonathan R. Yeh
Donovan Chan
Mylène Landry
Makoto C. Nagano
Jacquetta M. Trasler

STUDY QUESTION How does haploinsufficiency of the paternal-effect gene Dnmt3L affect DNA methylation establishment and stability in the male germline?

Keywords:

Methylation
DNA hypomethylation
DNA methylation
Germline
Epigenetics
Gene
Biology
Haploinsufficiency
Genetics
Paternal Inheritance
Molecular biology
Germ cell
DNA methyltransferase
Restriction landmark genomic scanning

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