Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion
2014
The presynaptic LAR-RPTPs interact with postsynaptic Slitrks and this contributes to regulating synapse formation. Here, the authors identified the minimal binding regions and determined the crystal structure of the resulting complex and performed functional analysis in cells to determine LAR-RPTP/Slitrk complex-mediated synapse formation.
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