Pseudothrombocytopenia After Abciximab (ReoPro) Treatment

A46-year-old man received a bolus and continuous infusion of abciximab (ReoPro) after PTCA. A platelet count before the procedure was 270 000/μL. Two hours after the bolus, an automated platelet count from EDTA blood was 92 000/μL (Figure 1⇓). The abciximab infusion was stopped. Four hours after the bolus, the platelet count from EDTA blood was 51 000/μL; at the same time, an automated platelet count from citrated blood was 215 000/μL. A peripheral blood film from EDTA blood (Figure 2⇓) showed marked platelet clumping, which was not present on a …