P12.16: Omphalocele; comparison of perinatal outcome following a prenatal diagnosis or a diagnosis at birth

Results: 189 fetuses showed a non-visible or nearly empty stomach at the time of the scan. 54 fetuses showed additional malformations, which resulted in termination of pregnancy. In 135 fetuses NVS was an isolated abnormality. Postnatally, 2 of 135 neonates (1,48%) showed TEF. In one of those two fetuses with TEF, polyhydramnios developed in the 3rd trimester of pregnancy like in 20/133 fetuses, who did not show TEF after birth. Conclusion: Statistically the risk of TEF is elevated 50fold in cases of NVS in the second trimester of pregnancy (0.03 vs. 1.5%). In most cases of isolated NVS, the child is healthy and only 1.48% of fetuses showed TEF postnatally. A detailed scan is recommended in the third trimester in cases of NVS to detect polyhydramios and to search for direct signs of TEF like the pouch sign or the distance aorta/left atrium of the heart. Postnatally TEF should be ruled out after NVS during pregnancy to avoid aspiration pneumonia in the affected neonates.