An Experimental Study of the Anti-inflammatory Effect of Xiaoertuiretie (Antipyretic Strapping for Children)

Objective:To appraise the anti inflammatory effect of Xiaoertuiretie . Method:With reference to relevant literature, two mouse models were set up, namely, inflammatory edema of the auricular concha caused by dimethylbenzene and increased permeability of abdominal capillaries resulted from the action of acetic acid. The mice were randomly divided into 5 groups, subjecting to large, medium and small dosages of Xiaoertuiretie strapping, 0.9% sodium chloride solution and prednisolone acetate (administered by stomach tubes) treatment, respectively. The animals were sacrificed after the treatment. The extent of inflammatory ear swelling and the absorbance of abdominal lavage fluid were determined so as to assess the anti inflammatory effect of Xiaoertuiretie . Results: Xiaoertuiretie was shown to exert a dramatic inhibitory effect on the inflammation of mouse's ear caused by dimethylbenzene and the increased permeability of capillaries in the abdominal cavity of the mouse caused by acetic acid. Conclusion: Xiaoertuiretie has a remarkable anti-inflammatory effect.