A phase I trial of intraperitoneal nab-paclitaxel in the treatment of advanced malignancies primarily confined to the peritoneal cavity

Mihaela C. Cristea,Paul Frankel,Timothy W. Synold,Saul E. Rivkin,Dean Lim,Vincent Chung,Joseph Chao,Mark T. Wakabayashi,Benjamin Paz,Ernest S. Han,Paul Lin,Lucille Leong,Amy Hakim,Mary Carroll,Neal Prakash,Thanh H. Dellinger,Min Park,Robert J. Morgan

A phase I trial of intraperitoneal nab-paclitaxel in the treatment of advanced malignancies primarily confined to the peritoneal cavity

2019

Mihaela C. Cristea
Paul Frankel
Timothy W. Synold
Saul E. Rivkin
Dean Lim
Vincent Chung
Joseph Chao
Mark T. Wakabayashi
Benjamin Paz
Ernest S. Han
Paul Lin
Lucille Leong
Amy Hakim
Mary Carroll
Neal Prakash
Thanh H. Dellinger
Min Park
Robert J. Morgan

Purpose To evaluate intraperitoneal (IP) nab-paclitaxel in patients with advanced malignancies that are primarily confined to the peritoneal cavity in a phase I trial.

Keywords:

Nab-paclitaxel
Pharmacology
Peritoneal cavity
Medicine
Ovarian cancer
Gastroenterology
Abdominal pain
Internal medicine
Neutropenia
Therapeutic index
Adverse effect
Cohort
Pharmacokinetics

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