Rana chensinensis extracted mixed liquid and application thereof in preparing medicines for treating and preventing dermatophytosis

2014 
The invention provides a rana chensinensis extracted mixed liquid and an application thereof in preparing medicines for treating and preventing dermatophytosis, and belongs to the technical field of medical bio-pharmacy. The mixed liquid is prepared by adopting the following steps: performing impurity-removal and dust-collection on dried rana chensinensis, crushing, adding complex enzyme hydrolysate, and centrifuging to obtain upper supernate; grinding remaining mixture, shearing, and drying by means of spray to obtain powder; adding the superfine powder into acetic acid, performing ultrasonic treatment, and filtering by virtue of a gauze element, centrifuging to obtain supernate, and concentrating at reduced pressure so as to obtain a mixture of polysaccharide, antimicrobial peptide and calcium ions; and mixing all the materials to obtain the rana chensinensis extracted mixed liquid. The mixed liquid is a pure biological preparation, and does not have side effect; micromolecular antimicrobial peptide with a remarkable antibacterial effect is combined with the calcium ions to reinforce destruction of the micromolecular antimicrobial peptide to fungal cell walls, and can enter fungal cells to achieve the antimicrobial effect; the oligopeptide collagen can enter normal cells in the action of polysaccharide to give sufficient nutrition to the cells, reinforce the defending function of the cells, helping the normal cells defend external damage factors and repairing injured cells.
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