Iridium-Catalyzed Decarboxylative N-Alkylation of α-Amino Acids with Primary Alcohols

A new decarboxylative N-alkylation reaction of α-amino acids has been developed. A variety of tertiary amines were obtained in good to excellent yields via the decarboxylative N - alkylation reaction of α-amino acids with primary alcohols catalyzed by a Cp*Ir complex.