Immune Modulation by Adjuvants Combined with Diphtheria Toxoid Administered Topically in BALB/c Mice After Microneedle Array Pretreatment

Zhi Ding,Y. E. van Riet,Stefan Romeijn,Gideon Kersten,Wim Jiskoot,J.A. Bouwstra

Immune Modulation by Adjuvants Combined with Diphtheria Toxoid Administered Topically in BALB/c Mice After Microneedle Array Pretreatment

2009

Zhi Ding
Y. E. van Riet
Stefan Romeijn
Gideon Kersten
Wim Jiskoot
J.A. Bouwstra

Purpose In this study, modulation of the immune response against diphtheria toxoid (DT) by various adjuvants in transcutaneous immunization (TCI) with microneedle array pretreatment was investigated.

Keywords:

Immune system
Adjuvant
Immunology
Diphtheria
Toxoid
Antigen
Virology
Diphtheria toxin
Medicine
BALB/c
immune modulation

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