MP14-03 DENSITY OF T-BET POSITIVE T LYMPHOCYTES WITHIN THE TUMOR MICROENVIRONMENT IS ASSOCIATED WITH A FAVORABLE RESPONSE TO IMMUNOTHERAPY IN PATIENTS WITH METASTATIC RENAL CELL CARCINOMA

Ali Hajiran,Ahmet Aydin,Young-Chul Kim,Logan Zemp,Susan McCarthy,Carlos Moran Segura,Johnathan Nguyen,Shayan Falasiri,Saif Zaman,Philippe E. Spiess,Manish Kohli,James J. Mulé,Brandon Manley

MP14-03 DENSITY OF T-BET POSITIVE T LYMPHOCYTES WITHIN THE TUMOR MICROENVIRONMENT IS ASSOCIATED WITH A FAVORABLE RESPONSE TO IMMUNOTHERAPY IN PATIENTS WITH METASTATIC RENAL CELL CARCINOMA

2020

Ali Hajiran
Ahmet Aydin
Young-Chul Kim
Logan Zemp
Susan McCarthy
Carlos Moran Segura
Johnathan Nguyen
Shayan Falasiri
Saif Zaman
Philippe E. Spiess
Manish Kohli
James J. Mulé
Brandon Manley

INTRODUCTION AND OBJECTIVE:The recent success of anti-PD1 therapeutics is known to be associated with an upregulated Th1 gene signature and an immunogenic tumor microenvironment (TME). There remain...

Keywords:

Immunotherapy
Tumor microenvironment
Cancer research
in patient
FAVORABLE RESPONSE
Pathology
Renal cell carcinoma
Medicine

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