Effect of Osmotic Opening of Blood-Brain Barrier on the Learning of Rats

T. Nagashima,Michio Yamaguchi,Isao Kinoshita,Hisahiko Suzuki,S. Chakarabortty,N. Tamaki

Effect of Osmotic Opening of Blood-Brain Barrier on the Learning of Rats

1993

T. Nagashima
Michio Yamaguchi
Isao Kinoshita
Hisahiko Suzuki
S. Chakarabortty
N. Tamaki

Osmotic opening of the blood brain barrier (BBB) has been used in the chemotherapy of brain tumors [2]. However, the potential risk of the procedure is still controversial [4, 5]. The purpose of the present study is to determine the effect of osmotic opening of BBB on learning of rats.

Keywords:

Blood–brain barrier
Evans Blue
Pathology
Chemotherapy
Malignant brain tumor
Medicine
Pharmacology
avoidance learning
potential risk

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