Application of rheum emodi wall extract to preparation of medicines for resisting ischemic cerebral vascular diseases

2012 
The invention discloses new application of a rheum emodi wall extract, and particularly relates to application of the rheum emodi wall extract to the preparation of medicines for preventing and treating ischemic cerebral vascular diseases. Animal experiments prove that an extract which is prepared from rheum emodi wall, is percolated, leached and eluted by using ethanol and 3,5,3',4'-tetrahydroxystilbene-4'-O-beta-D-glucopyranoside can relieve the neuromotor dysfunction of rats subjected to middle cerebral artery occlusion, reduce the range of cerebral infarction, have an effect of relieving the ischemic cerebral vascular diseases, and can achieve the protective effect on the ischemic cerebral tissues by lowering the level of tumor necrosis factors and the expression level of fatty acid synthase (Fas) protein. Therefore, the rheum emodi wall extract has the obvious treatment effect on the ischemic cerebral vascular diseases of experimental animals, which are caused by multiple reasons, and can be applied to the preparation of the medicines for treating or preventing the ischemic cerebral vascular diseases.
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