Proteasome-Dependent Regulation of Distinct Metabolic States During Long-Term Culture of Human iPSC-Derived Cardiomyocytes

Antje D. Ebert,Amit U. Joshi,Sandra Andorf,Yuanyuan Dai,Shrivatsan Sampathkumar,Haodong Chen,Yingxin Li,Priyanka Garg,Karl Toischer,Gerd Hasenfuss,Daria Mochly-Rosen,Joseph C. Wu

Proteasome-Dependent Regulation of Distinct Metabolic States During Long-Term Culture of Human iPSC-Derived Cardiomyocytes

2019

Antje D. Ebert
Amit U. Joshi
Sandra Andorf
Yuanyuan Dai
Shrivatsan Sampathkumar
Haodong Chen
Yingxin Li
Priyanka Garg
Karl Toischer
Gerd Hasenfuss
Daria Mochly-Rosen
Joseph C. Wu

Rationale: The immature presentation of human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) is currently a challenge for their application in disease modeling, drug screening, and...

Keywords:

Cardiology
Induced pluripotent stem cell
Diabetes mellitus
Disease
Biology
Internal medicine
Human Induced Pluripotent Stem Cells
Drug
Cell biology
Proteasome
Homeostasis
Regenerative medicine
Mitochondrion

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