MP27-18 INTRAOPERATIVE USE OF BETADINE IRRIGATION IS ASSOCIATED WITH A 9-FOLD INCREASE OF PENILE PROSTHESIS INFECTION

INTRODUCTION AND OBJECTIVES:Infection remains a persistent complication of inflatable penile prosthesis (IPP) surgery. Despite popularity of the Mulcahy IPP washout protocol, Betadine has known tissue toxicity. We evaluated IPP infection rate based on the type of intraoperative irrigation utilized, Betadine (10%) versus Vancomycin / Gentamicin, and other factors which may affect infection rate.METHODS:We reviewed a consecutive series from a detailed, prospective database of men undergoing primary, revision, and salvage penile prostheses at our institution. The primary outcome was rate of IPP infection prior to and following change of intra-operative irrigation. No other changes to operative or perioperative techniques occurred following the change in irrigation solution. Univariate and regression analyses were used to evaluate differences in infection rate with use of Betadine versus Vancomycin/Gentamicin irrigation. Multiple potential confounders were reviewed including patient demographics, comorbiditie...