Нейрогуморальные и психоэмоциональные аспекты гипертонической болезни

87 participants of the study aged 30−60 years suffered from arterial hypertension of grade I-II, with low, moderate and high overall cardiovascular risk. Average age of patients was 47,7 ± 7,4 years old and average disease duration was 11,1 ± 9,4 years. Level of serotonin and adrenoreactivity by a method based on erythrocyte osmoresistance change under beta blockers influence were evaluated in all patients. Psychoemotional features were assessed by psychological testing. The performed study showed elevated adrenoreactivity and plasma serotonin level in more than 50% of cases. According to our study all patients suffering from arterial hypertension can be divided in 3 groups depending on psychoemotional status: 1st group patients with high aggressiveness; 2nd group patients with high situative and personal anxiety and high hostility; 3d group patients without changes in psychoemotional status. Results of the study confirm the fact that psychoemotional status dysfunction is encountered in 67,8% while 32,2% of patients do not demonstrate significant changes of emotional profile