N-(Triisopropylsilyl)pyrrole. A Progenitor “Par Excellence” of 3- Substituted Pyrroles.

A most useful strategy has been devised for the synthesis of 3-substituted pyrroles on the basis of the kinetic electrophilic substitution of 1-(triisopropylsilyl) pyrrole (1) at the β position and subsequent fluoride ion induced desilylation. This now becomes the preferred route to 3-monosubstituted pyrroles