Anti-Fibrosis Effect of Relaxin and Spironolactone Combined on Isoprenaline-Induced Myocardial Fibrosis in Rats via Inhibition of Endothelial–Mesenchymal Transition

Jiejie Cai,Xi Chen,Lingzhi Chen,Zheng G,Hong-Hao Zhou,Xuedong Zhou

Anti-Fibrosis Effect of Relaxin and Spironolactone Combined on Isoprenaline-Induced Myocardial Fibrosis in Rats via Inhibition of Endothelial–Mesenchymal Transition

2017

Jiejie Cai
Xi Chen
Lingzhi Chen
Zheng G
Hong-Hao Zhou
Xuedong Zhou

Background: The effect of relaxin and spironolactone combined on myocardial fibrosis has not been reported. Thus, we investigated the effect of the combined thera

Keywords:

Isoprenaline
Biochemistry
Fibrosis
Cardiac fibrosis
Spironolactone
Diabetes mellitus
Endocrinology
Mesenchymal stem cell
Biology
Internal medicine
Relaxin
myocardial fibrosis
anti fibrosis

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