Observations on salicyl hydroxamic acid, an experimental trypanocide

A.J. Barnicoat,W.G.van T. Hoff,P. J. Morrison,H. J. Rogers

Observations on salicyl hydroxamic acid, an experimental trypanocide

1981

A.J. Barnicoat
W.G.van T. Hoff
P. J. Morrison
H. J. Rogers

The inferior in vivo efficacy of salicyl hydroxamic acid against trypanosomiasis may be explained by its short half-life, high degree of protein binding and low tissue levels.

Keywords:

In vivo
Hydroxamic acid
Biochemistry
Plasma protein binding
Trypanosomiasis
Biology
Organic chemistry
Stereochemistry

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