An Endemic Challenge of Dengue - a Crucial Review

Dengue fever is a serious threat to global health issues; it leads us to a public health challenge with an economic saddle. Approximately 100 countries are endemic for dengue fever and 40% of the world's population or about 2.5 billion people in the tropical and sub-tropics have an increased risk. It is also known break bone fever, is a selflimited, systematic viral infection transmitted from mosquitoes to humans.. Symptoms include fever, headache, muscle and joint pains, and with a characteristic skin rashes that is similar to measles. In a small proportion of cases, the disease develops into the life-threatening dengue hemorrhagic fever, resulting in bleeding, low levels of blood platelets and blood plasma leakage, or into dengue shock syndrome. To the core of this review are ought to discuss about the symptoms, mechanism of the virus in the host, penetration towards our body, characteristic antibody responses, life cycle, various phases involved in the cycle, efficient vector control strategies, pathogenesis, Diagnosis, ongoing therapies, and its management and prevention.