Suppression of cardiac autophagy by hyperinsulinemia in insulin receptors deficient hearts is mediated by insulin-like growth factor receptor signaling

Karla Maria Pereira Pires,Natalia S. Torres,Marcio Buffolo,River Gunville,Christin L. Schaaf,Kathryn Davis,Craig H. Selzman,Roberta A. Gottlieb,Sihem Boudina

Suppression of cardiac autophagy by hyperinsulinemia in insulin receptors deficient hearts is mediated by insulin-like growth factor receptor signaling

2019

Karla Maria Pereira Pires
Natalia S. Torres
Marcio Buffolo
River Gunville
Christin L. Schaaf
Kathryn Davis
Craig H. Selzman
Roberta A. Gottlieb
Sihem Boudina

Aims: Autophagy is a catabolic process required for the maintenance of cardiac health. Insulin and insulin-like growth factor 1 (IGF-1) are potent inhibitors of autophagy and as such, one would pre...

Keywords:

Cell biology
Insulin-Like Growth Factor Receptor
Biology
Hyperinsulinemia
Insulin receptor
Autophagy
Insulin
Growth factor
Catabolic Process

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