Dynamics of tumor response in advanced melanoma patients treated with Coxsackievirus A21.

Robert Hans Ingemar Andtbacka,Brendan D. Curti,Howard L. Kaufman,John Nemunaitis,Gregory A. Daniels,Sigrun Hallmeyer,Eric D. Whitman,Jose Lutzky,Stephen Schultz,Lynn E. Spitler,Zipei Feng,Christopher Paustian,Bernard A. Fox,Carlo Bifulco,Karl Zhou,Mark Grose,Darren R. Shafren

Dynamics of tumor response in advanced melanoma patients treated with Coxsackievirus A21.

2016

Robert Hans Ingemar Andtbacka
Brendan D. Curti
Howard L. Kaufman
John Nemunaitis
Gregory A. Daniels
Sigrun Hallmeyer
Eric D. Whitman
Jose Lutzky
Stephen Schultz
Lynn E. Spitler
Zipei Feng
Christopher Paustian
Bernard A. Fox
Carlo Bifulco
Karl Zhou
Mark Grose
Darren R. Shafren

9553Background: CAVATAK, an oncolytic immunotherapy, is a bio-selected oncolytic strain of Coxsackievirus A21 (CVA21). Intratumoral (IT) injection of CVA21 induces lytic tumor cell infection, up-re...

Keywords:

Melanoma
Coxsackievirus A21
Pathology
Oncology
Internal medicine
Medicine
Immunotherapy
tumor response
advanced melanoma
Oncolytic virus
Lytic cycle
Cancer research
tumor cells

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