013 In patients with normal perfusion imaging, is there a relationship between calcium score and myocardial flow reserve?

tients were excluded (3 as they were unable to tolerate CMR, 1 patient due to being unable to breath hold during adenosine and 1 patient due to significant artifact from an abdominal surgical clip) leaving 25 patients (average age 61 10 years) for analysis. There were 800 myocardial segments (baseline and with adenosine) available for analysis, 278 of these segments were subtended by a coronary artery with an available FFR value. Seventy-seven segments (28%) were excluded due to pre-defined criteria for poor image quality, 53 (69%) of these segments were during adenosine and 48 (62%) were apical segments. From the remaining seventyfive paired segments (75 segments at baseline and 75 segments during adenosine), 38 had FFR values 0.80, 37 had FFRs of 0.80. Mean percent SI change was significantly less in segments with abnormal FFR values (0.23% 9.40%), in comparison to patients with normal FFR values (8.58% 9.58%; P 0.0002). CONCLUSION: A blunted hyperemic response to adenosine detected with BOLD-sensitive CMR using a 1.5T scanner can identify functionally significant coronary artery stenosis. However, image quality remains a limitation of the approach. Most excluded segments were from early studies, suggesting improved acquisition quality with experience.