MULTIPLE HORMONAL AND METABOLIC DEFICIENCY SYNDROME REDUCES SURVIVAL IN CHRONIC HEART FAILURE: THE TOSCA REGISTRY

Multiple hormonal deficiency syndrome (MHDS) is common in heart failure (HF). To date, no large observational study has unequivocally demonstrated that MHDS impacts on HF progression. Aim of the T.O.S.CA. Registry ([NCT02335801][1]) was to test whether MHDS affects morbidity and mortality in a large