Sensitization of the leukocytes of stomach cancer patients to extracts of the tumor
1985
: The parallel LAI-tests using tumor cell (Tu) and normal mucosa (Muc) extracts were run in cases of gastric carcinoma (110), benign lesions of the stomach (46) and healthy controls (33). A high incidence (37-43%) of positive reactions in mucosa extract series was observed in both groups of patients. Four possible types of the response were analysed: Tu + Muc+, Tu--Muc--, Tu+Muc- and Tu--Muc+. The peak of Tu--Muc+ type reactivity was observed at stage III of the disease (p less than 0.05). Response to Tu extracts only (Tu+Muc--) was registered mainly in cancer patients but never occurred in the benign group. The best prognosis was observed in cases of Tu+Muc+ type response (p less than 0.02).
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