Competitive Adsorption of Albumin, Fibronectin and Collagen Type I on Different Biomaterial Surfaces: A QCM-D Study

Adsorption of several proteins, individually and in a mixture, onto substrates was investigated. Five biomaterial surfaces were selected based on their functionality and/or hydrophilicity: Ti6Al4V, Ti6Al4V + poly(sodium styrene sulfonate) (poly(NaSS)), gold, poly(desamino tyrosyltyrosine ethyl ester carbonate) (poly(DTE)), polystyrene (PS). Their ability to interact with BSA, Fn and Col I was studied using a QCM-D technique.