Structural evidence for an essential Fe-S cluster in the catalytic core domain of DNA polymerase ε.
2019
DNA polymerase ϵ (Pol ϵ), the major leading-strand DNA polymerase in eukaryotes, has a catalytic subunit (Pol2) and three non-catalytic subunits. The N-terminal half of Pol2 (Pol2CORE) exhibits bot ...
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