COVID-19 Vaccination acceptance in the canton of Geneva: A Cross-Sectional Population-Based Study

Abstract Objective This study aimed to assess acceptance of COVID-19 vaccination as well as its sociodemographic and clinical determinants in a general population sample three months after the launch of the vaccination program in Switzerland. Methods In March 2021, an online questionnaire on vaccination acceptance was proposed to adults included in a longitudinal cohort study of previous population-based serosurveys carried out in the canton of Geneva. Questions were asked about COVID-19 vaccination acceptance, reasons of acceptance or refusal, and attitudes about vaccination in general. Data on demographic (age, sex, education, income, professional status, living conditions) and health-related characteristics (having a chronic disease, COVID-19 diagnosis, smoking status) were assessed at inclusion in the cohort (December 2020). Results Overall, 4’067 participants (completion rate of 77.4%) responded to the survey between March 17 and April 1, 2021. The mean age of respondents was 53.3 years and 56.0% were women. Most had completed tertiary education (64.7%) and over 60% were currently professionally active. At the time of the survey, 17.2% of respondents had already been vaccinated with at least one dose or had made an appointment to get vaccinated, and an additional 58.5% intended or rather intended to get vaccinated. The overall acceptance of COVID-19 vaccination was 75.7%, with a higher acceptance among men compared to women, older adults compared to younger adults, high-income individuals compared to those with a low income, participants living in urban and semi-urban areas compared to rural, and retirees and students compared to employed individuals. Acceptance was lower among individuals having completed apprenticeships and secondary education compared to those with tertiary education. The most common reasons reported by participants intending to get vaccinated were the desire to ‘get back to normal’, to protect themselves, their community and/or society, and their relatives or friends against the risk of infection by SARS-CoV-2, as well as the desire to travel. Less than half (45.6%) of participants having children were willing or rather willing to have their children vaccinated against COVID-19 if it were recommended by public health authorities. Conclusion Although our study found a 75.7% acceptance of COVID-19 vaccination, there were noticeable socio-demographic disparities in vaccination acceptance. These data will be useful for public health measures targeting hesitant populations when developing health communication strategies. These results will be updated over time with a new release of the survey in autumn 2021.