Biophysical analysis of membrane proteins : investigating structure and function

Introduction STRUCTURAL APPROACHES Membrane Protein Structure Determination by Electron Cryo-microscopy NMR Liquid or Solid State MOLECULAR INTERACTION AND LARGE ASSEMBLIES Analytical Ultracentrifugation: Membrane Protein Assemblies in the Presence of Detergent SPR Biosensors for Characterizing Membrane-associated Proteins Atomic Force Microscopy (AFM): High Resolution Imaging of Structure and Assembly of Membrane Proteins DYNAMICS Molecular Dynamics Simulations Understanding Structure and Function of Membrane Proteins Using Free Energy Calculations Neutron Scattering to Study Membrane Structure and Dynamics SPECTROSCOPIES Circular Dichroism: Folding and Conformational Changes of Membrane Proteins Membrane Protein Structure and Conformational Change Probed Using Fourier Transform Infrared Spectroscopy Raman Spectroscopy on Light Harvesting Complex EXPLORING STRUCTURE-FUNCTION RELATIONSHIPS IN WHOLE CELLS Energy Transfer Technologies to Monitor the Dynamics and Signaling Properties of G-protein Coupled Receptors in Living Cells