Usefulness and limitations of determination of lactate dehydrogenase enzymes in the diagnosis of liver diseases

: Serum LDH isoenzyme electrophoretic pattern was evaluated in forty-four patients affected by acute or chronic liver diseases. Moreover, the correlation between LDH4, LDH5, and various parameters of liver function (particularly SGOT and SGPT) were examined. The authors believe that LDH4 and LDH5 are useful parameters for the differential diagnosis between chronic persistent hepatitis and chronic active hepatitis.