Symptomatic spinal cord metastasis of glioblastoma multiforme

2012 
Metastases espinhais sintomaticas de glioblastoma multiforme sao raramente descritas na literatura. Relatamos o caso de um paciente de 27 anos que apresentou quadro de dor lombar e em membros inferiores bilateralmente nove meses apos diagnostico de GBM intracraniano. Exame de ressonância magnetica da coluna lombar mostrou tumor em L1-L2 que foi removido com sucesso, e analise anatomopatologico foi consistente com metastase de GBM. Metastase espinhal deve ser investigada e incluida no diagnostico diferencial de paciente com historia previa de GBM intracraniano e queixa de sintomas espinhais. Symptomatic spinal cord metastasis from glioblastomamultiforme (GBM) has rarely been reported in the literature.We report the case of a 27-year-old man that presented withback and bilateral leg pain nine months after the primarydiagnosis of intracranial GBM. A magnetic resonance imaging(MRI) of the lumbar spine showed a L1-L2 tumor that wasremoved successfully and histopathological examination wasconsistent with GBM metastasis. Spinal metastasis shouldbe investigated and included in the differential diagnosis if apatient with a previous history of intracranial GBM presentswith spinal symptoms.
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