Effect of allopurinol on tissue ATP, ADP and AMP concentrations in renal ischaemia

The effect of allopurinol on the concentrations of A TP, ADP and AMP in rat kidneys during ischaemia and postischaemic recovery was studied. Significantly higher concentrations of ATP, ADP and AMP were maintained in the allopurinol-treated animals as compared with the control animals during ischaemic and postischaemic recovery.