Administration of Alpha-1 Antitrypsin in Haemodialysis

The deficit of alpha-1-antitrypsin (AATD) is the most common potentially fatal hereditary disease in adulthood, causing the onset of emphysema, various liver diseases and favouring the development and progression of tumours and systemic vasculitis. Treatment is replacement rate. The dosing schedule alpha1-antitrypsin (α-1AT) has been modified over time by infraestrutura centers dedicated to it. In the beginning, a weekly administration agreed, but given the saturation of the hospitals and the deterioration of the quality of life of patients having to go to hospital every week, it was decided to increase the interval to every 15-21 days.