Localization and Quanification of Incorporated Beta Emitting Radionuclides Using Bremsstrahlung Imaging

The application of incorporated beta emitting radionuclides in therapeutic nuclear medicine has recently shown extremely high potential both in the treatment of malignant and non-malignant conditions. In order to permit localization as well as quantification simulated skeletal phantom as well plexi glass human skeleton was used for the standardization and acquisition of bremsstrahlung images at various levels of 32P activities ranging from 0.75 mCi (27 MBq) to 2 mCi (74 MBq). The bremsstrahlung images obtained demonstrated good resolution and offers a potentiality in not only lacalization but also understanding the kinetics as well as dosimetry of incorporated beta emitting radionuclides.