Association between the tumor necrosis factor-α −308 G/A gene polymorphism and migraine

In a group of 299 migraine patients and 306 control subjects, the association of the −308 G/A polymorphism in the tumor necrosis factor-α gene (TNFα) with the occurrence and clinical characteristics of migraine was tested. Homozygosity for the G allele was associated with an increased risk of migraine (odds ratio [OR] = 2.85, p p