The clinical significance of skeletal scintigraphy in the management of carcinoma

Abstract The majority of skeletal metastases originate via localization in the bone marrow. A study of the various 99 Tc m polyphosfate complexes available for skeletal scintigraphy suggests that the use of short chain polyphosphates with a significant bone marrow uptake is advantageous in detecting skeletal metastases at an early stage.