Prediction of human bioavailability from human oral administration data and animal pharmacokinetic data without data from intravenous administration of drugs in humans.

Haruo Imawaka,Kiyomi Ito,Yoshiaki Kitamura,Kiyoshi Sugiyama,Yuichi Sugiyama

Prediction of human bioavailability from human oral administration data and animal pharmacokinetic data without data from intravenous administration of drugs in humans.

2009

Haruo Imawaka
Kiyomi Ito
Yoshiaki Kitamura
Kiyoshi Sugiyama
Yuichi Sugiyama

Purpose To predict the absolute oral bioavailabilities (BAs) of drugs in humans without using pharmacokinetic data from intravenous administration in humans.

Keywords:

Drug
Volume of distribution
Oral administration
Bioavailability
Pharmacology
Pharmacokinetics
Medicine
pharmacology toxicology
pharmaceutical technology

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