An eight-week randomised controlled trial of home-based pilates for symptoms of anxiety, depression, and fatigue among people with MS with minimal-to-mild mobility disability: Study protocol

Abstract Background Evidence supports positive effects of exercise on mental health outcomes among people with Multiple Sclerosis (PwMS). However, non-traditional exercise modes like Pilates remain understudied. Objective This study will investigate the effects of an eight-week immediate start home-based Pilates compared to delayed-start control condition on symptoms of anxiety, depression, and fatigue among PwMS. Methods 68 adults (>18 years old) with physician diagnosed Multiple Sclerosis, Patient Determined Disease Steps (PDDS) score Conclusion This randomised controlled trial will provide additional information regarding the feasibility of Pilates to improve mental health outcomes, and the magnitude of the effects of Pilates compared to a wait-list control on mental health outcomes among PwMS. These findings should inform both healthcare professionals and exercise scientists regarding the potential of home-based Pilates to improve management of several mental health symptoms prevalent among PwMS.