THRESHOLD FOR THE EFFECTS OF ACTH ON BLOOD PRESSURE IN SHEEP

SUMMARY 1. The time of onset and dose threshold for ACTH induced hypertension was examined in conscious sheep. 2. ACTH 1 μg/kg per day significantly raised blood pressure. The maximum rise occurred at 2 μg/kg per day. 3. The rise in pressure was significant after 8 h of ACTH infusion.