The Influence of Polysorbate 80 on the Radiochemical Synthesis of a PET Tracer in the FASTlab

Wai Lam Yip,Sverre Arne Sande,David Grace,Dirk-Jan In't Veld,Per Christian Sontum,Tina Solvang,Knut Dyrstad

The Influence of Polysorbate 80 on the Radiochemical Synthesis of a PET Tracer in the FASTlab

2015

Wai Lam Yip
Sverre Arne Sande
David Grace
Dirk-Jan In't Veld
Per Christian Sontum
Tina Solvang
Knut Dyrstad

Purpose The aim of current study was to investigate the influence of a common non-ionic surfactant, polysorbate 80 (PS80), on radioactive labelling process of a novel PET tracer, [18F]Flutemetamol.

Keywords:

Polysorbate 80
Biochemistry
Chemistry
Chromatography
pet tracer
Pulmonary surfactant
Labelling
pharmacology toxicology

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