Synthesis of homochiral bis (oxazolinyl) pyridine type ligands for asymmetric cyclopropanation reactions

Abstract Homochiral bis(oxazolinyl)pyridine type ligands were synthesized from ( S )-valine and converted into their Cu(II) complexes. Reduction of these Cu(II) complexes into Cu(I) with diazoesters was studied by uv-vis and epr spectroscopy. The enantioselective cyclopropanation reaction was carried out using styrene as a model substrate.