Y chromosome specific STR testing and the US legal system
2000
An improved method of preparing acid addition salts of dl 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole (dl-tetramisole) by reacting dl-3-( beta -hydroxyphenethyl)-2-iminothiazolidine or an acid-addition salt thereof, with a mixture of concentrated hydrochloric acid and concentrated sulfuric acid to obtain dl 3-( beta -chlorophenethyl)-2-iminothiazolidine acid-addition salt, treating this compound with aqueous alkali to obtain dl 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole free base, and converting the latter compound to dl 6-phenyl-2,3,5,6-tetrahydroimidazo [2,1-b]thiazole acid-addition salts in a highly purified state. The products are useful as anthelmintics.
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