The value of antibodies against mutated citrullinated vimentin in juvenile idiopathic arthritis

Materials and methods We analysed 41 patients with newly diagnosed JIA (25 RF negative polyarthritis, 10 oligoarthritis, 5 undifferentiated and 1 psoriatic arthritis). To evaluate disease activity, clinical (disease type, number of active and inactive joints) and laboratory (CRP, ESR, TNF alfa, ANA titer, HLA B 27 antigen) data were recorded. The level of anti-MCV in the sera of JIA patients and 21 controls (healthy chidren with no family history of any rheumatological disease) was measured using ELISA method (Orgenetic Diagnostica, GbmH, Germany). For statistical analysis we used T test and Mann-Whitney test.