SNP typing of crime case samples with the SNPforID multiplex assay

Abstract The SNP for ID multiplex was tested on typical crime case samples. In a mixture study, both controlled experiments with samples mixed in known ratios and a blind study were conducted. All mixtures were identified, including samples mixed in 1:40 ratios. For the study of degraded DNA, 50 crime case samples were selected. Complete SNP profiles were obtained in 80% of the highly degraded samples and at least 41 SNPs were typed in the last 20%. Furthermore, 30% of the highly degraded samples turned out to be mixtures.