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Scale-Up and Optimization of a Continuous Flow Carboxylation of N-Boc-4,4-difluoropiperidine Using s-BuLi in THF
Scale-Up and Optimization of a Continuous Flow Carboxylation of N-Boc-4,4-difluoropiperidine Using s-BuLi in THF
2021
Jean-Paul Kestemont
James R. Frost
Jerome Jacq
Patrick Pasau
Frédéric Perl
Julien Brown
Matthieu Tissot
Keywords:
continuous flow
Carboxylation
SCALE-UP
Medicinal chemistry
Materials science
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