Quantum dot-labeled trichosanthin
2000
Semiconductor quantum dots have been used for the first time
to label trichosanthin. The absorption and fluorescent spectra of quantum
dot-labeled trichosanthin were different from those of trichosanthin, but
no changes were found in the enzymatic activity of quantum dot-labeled
trichosanthin in comparison with trichosanthin. The distribution of quantum
dot-labeled trichosanthin in the cytoplasm of a human choriocarcinoma cell
is observed with two-photon laser scanning microscopy, and the aggregation
of quantum dot-labeled trichosanthin in the cytoplasm is discussed.
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