Rhodium-catalyzed NH-indole-directed ortho C H coupling of 2-arylindoles with diazo compounds via metal carbene migratory insertion

Abstract A high regioselective rhodium-catalyzed ortho C H coupling of 2-arylindoles with diazo compounds via NH-indole-directed C H bond activation has been developed. The catalytic reaction features mild reaction conditions, broad substrate scope and good functional group tolerability.