Functional electrical stimulation exercise increases GLUT-1 and GLUT-4 in paralyzed skeletal muscle

Abstract The study purpose was to determine the effect of functional electrical stimulation (FES)-leg cycle ergometer training (30 minutes on 3 d/wk for 8 weeks) on the GLUT-1 and GLUT-4 content of paralyzed skeletal muscle. Biopsy samples of vastus lateralis muscle were obtained pre- and post-training from five individuals with motor-complete spinal cord injury ([SCI] four men and one woman aged 31 to 50 years, 3 to 25 years postinjury involving C5-T8. Western in blot analysis indicated that GLUT-1 increased by 52% and GLUT-4 increased by 72% with training ( P P P