Cancer, Lymphocyte Depleted Hodgkin Lymphoma

Lymphocyte-depleted classic Hodgkin lymphoma (LDCHL) is the rarest subtype of classic Hodgkin lymphoma (HL) in the Western world, although it may be more common in the developing countries.[1][2][3] The diagnosis of LDCHL could be challenging, and the disease might be misdiagnosed as more aggressive B-cell or T-cell lymphomas.[4] Patients with LDCHL present more often with unfavorable risk factors and have poorer survival rates than those with other subtypes of classic HL.[5][6]